COVID-19 breakthrough infections among people living with and without HIV: A statewide cohort analysis.

ABSTRACT:

Objectives

This study aims to characterize and compare COVID-19 breakthrough infections between people living with and without HIV across different phases of the pandemic.

Methods

Using statewide HIV cohort data, the study population included adult residents in South Carolina (SC) (>18 years old) who were fully vaccinated between January 02, 2021 and April 14, 2022 when Alpha, Delta, and Omicron variants were circulating in SC. We used the Cox proportional hazard model to investigate the association between HIV infection and breakthrough infection, adjusting for relevant covariates.

Results

Among 2,144,415 vaccinated individuals, 8,335 were people living with HIV (PLWH) and 2,136,080 were people without HIV (PWoH). After propensity score matching, HIV infection was no

SUBMITTER: Yang X 

PROVIDER: S-EPMC10842358 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature