Pelvic lymphadenectomy: Evaluating nodal stage migration and will rogers effect in bladder cancer.

ABSTRACT:

Introduction

Pelvic lymphadenectomy (PLND) alongside radical cystectomy (RC), provides crucial diagnostic and therapeutic value in patients with bladder cancer. With the advent of neoadjuvant chemotherapy and prospective data supporting standard PLND, controversy remains regarding the optimal PLND extent and patient selection. Nearly 40% of patients may not receive adequate PLND, even though 25% of patients have positive lymph nodes (LN) at time of RC. We hypothesized that PLND still remains an important facet of bladder cancer treatment. To clarify the prognostic importance of nodal yield, we performed a retrospective investigation of a heterogenous population (pTanyNx/0M0) of patients undergoing RC.

Methods

From the Surveillance, Epidemiology, and End Results (SEER) progra

SUBMITTER: Sodagum L 

PROVIDER: S-EPMC10842630 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature