The Medical Action Ontology: A tool for annotating and analyzing treatments and clinical management of human disease.

ABSTRACT:

Background

Navigating the clinical literature to determine the optimal clinical management for rare diseases presents significant challenges. We introduce the Medical Action Ontology (MAxO), an ontology specifically designed to organize medical procedures, therapies, and interventions.

Methods

MAxO incorporates logical structures that link MAxO terms to numerous other ontologies within the OBO Foundry. Term development involves a blend of manual and semi-automated processes. Additionally, we have generated annotations detailing diagnostic modalities for specific phenotypic abnormalities defined by the Human Phenotype Ontology (HPO). We introduce a web application, POET, that facilitates MAxO annotations for specific medical actions for diseases using the Mondo Disease Ontolo

SUBMITTER: Carmody LC 

PROVIDER: S-EPMC10842845 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature