Is nonoperative management of appendicitis safe and effective in multi-morbid patients?

ABSTRACT:

Background

The purpose of this study was to (1) compare post-treatment outcomes of operative and nonoperative management of acute appendicitis in multi-morbid patients and (2) evaluate the generalizability of prior clinical trials by determining whether outcomes differ in multi-morbid patients compared to the young and healthy patients who resemble prior clinical trial participants.

Methods

We conducted a retrospective cohort study using the National Inpatient Sample from 2004 to 2017. We included 368,537 patients with acute, uncomplicated appendicitis who were classified as having 0 or 2+ comorbidities. We compared inpatient morbidity, mortality, length of stay, and costs using propensity scores. Unmeasured confounding was addressed with probabilistic sensitivity analysis.<

SUBMITTER: Lunardi N 

PROVIDER: S-EPMC10842865 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature