Analysis of Radiation Therapy Quality Assurance in NRG Oncology RTOG 0848.

ABSTRACT:

Purpose

NRG/Radiation Therapy Oncology Group 0848 is a 2-step randomized trial to evaluate the benefit of the addition of concurrent fluoropyrimidine and radiation therapy (RT) after adjuvant chemotherapy (second step) for patients with resected pancreatic head adenocarcinoma. Real-time quality assurance (QA) was performed on each patient who underwent RT. This analysis aims to evaluate adherence to protocol-specified contouring and treatment planning and to report the types and frequencies of deviations requiring revisions.

Methods and materials

In addition to a web-based contouring atlas, the protocol outlined step-by-step instructions for generating the clinical treatment volume through the creation of specific regions of interest. The planning target volume was a uniform

SUBMITTER: Tchelebi LT 

PROVIDER: S-EPMC10843017 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature