Changes in leukocyte telomere length among children with obesity participating in a behavioural weight control program.

ABSTRACT:

Objective

To examine changes in leukocyte telomere length (LTL) during and after a behavioural weight control program for children with obesity.

Methods

We measured LTL among a cohort of 158 children 8-12 years of age with a body mass index greater than or equal to the 95th percentile for age and sex. Children were 55% female, 29% white, 52% Latinx, 8% Asian and 11% Pacific Islander, other or multiethnic. All children participated in a 6-month, family-based, group behavioural weight control program and were assessed before treatment, after treatment and 1 year after the end of treatment. To test the sample population slope of LTL over the intervention and maintenance time periods, we fit spline mixed-effect regression models.

Results

LTL increased an average of 0.09 T

SUBMITTER: Rehkopf DH 

PROVIDER: S-EPMC10843039 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature