Diminished measles immunity after paediatric liver transplantation-A retrospective, single-centre, cross-sectional analysis.

ABSTRACT: Liver transplantation in childhood has an excellent long-term outcome, but is associated with a long-term risk of infection. Measles is a vaccine-preventable infection, with case series describing severe courses with graft rejection, mechanical ventilation and even death in liver transplant recipients. Since about 30% of liver transplanted children receive liver transplants in their first year of life, not all have reached the recommended age for live vaccinations. On the contrary, live vaccines are contraindicated after transplantation. In addition, vaccination response is poorer in individuals with liver disease compared to healthy children. This retrospective, single-centre, cross-sectional study examines measles immunity in paediatric liver transplant recipients before and after transp

SUBMITTER: Laue T 

PROVIDER: S-EPMC10843477 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature