Whole knee joint mapping using a phase modulated UTE adiabatic T_1ρ (PM-UTE-AdiabT_1ρ ) sequence.

ABSTRACT:

Purpose

To develop a 3D phase modulated UTE adiabatic T_1ρ (PM-UTE-AdiabT_1ρ ) sequence for whole knee joint mapping on a clinical 3 T scanner.

Methods

This new sequence includes six major features: (1) a magnetization reset module, (2) a train of adiabatic full passage pulses for spin locking, (3) a phase modulation scheme (i.e., RF cycling pair), (4) a fat saturation module, (5) a variable flip angle scheme, and (6) a 3D UTE Cones sequence for data acquisition. A simple exponential fitting was used for T_1ρ quantification. Phantom studies were performed to investigate PM-UTE-AdiabT_1ρ 's sensitivity to compositional changes and reproducibility as well as its correlation with continuous wave-T_1ρ measurement. The PM-UTE-Adia

SUBMITTER: Ma Y 

PROVIDER: S-EPMC10843531 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature