Test-Retest Reliability of Functional Connectivity in Adolescents With Depression.

ABSTRACT:

Background

The test-retest reliability of functional magnetic resonance imaging is critical to identifying reproducible biomarkers for psychiatric illness. Recent work has shown how reliability limits the observable effect size of brain-behavior associations, hindering detection of these effects. However, while a fast-growing literature has explored both univariate and multivariate reliability in healthy individuals, relatively few studies have explored reliability in populations with psychiatric illnesses or how this interacts with age.

Methods

Here, we investigated functional connectivity reliability over the course of 1 year in a longitudinal cohort of 88 adolescents (age at baseline = 15.63 ± 1.29 years; 64 female) with major depressive disorder (MDD) and without MDD (he

SUBMITTER: Camp CC 

PROVIDER: S-EPMC10843837 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature