Silica-coated magnetic particles for efficient RNA extraction for SARS-CoV-2 detection.

ABSTRACT: Molecular diagnostic methods to detect and quantify viral RNA in clinical samples rely on the purification of the genetic material prior to reverse transcription polymerase chain reaction (qRT-PCR). Due to the large number of samples processed in clinical laboratories, automation has become a necessity in order to increase method processivity and maximize throughput per unit of time. An attractive option for isolating viral RNA is based on the magnetic solid phase separation procedure (MSPS) using magnetic microparticles. This method offers the advantage over other alternative methods of making it possible to automate the process. In this study, we report the results of the MSPS method based on magnetic microparticles obtained by a simple synthesis process, to purify RNA from oro- and naso

SUBMITTER: Capriotti N 

PROVIDER: S-EPMC10844049 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature