Atypical cerebellar activity and connectivity during affective touch in adults with skin-picking disorder.

ABSTRACT: Excessive touching and picking of one's skin are core symptoms of skin-picking disorder (SPD). Previous research has shown that patients with SPD display difficulties in motor control and show altered reward responsivity. Considering the limited knowledge about neuronal mechanisms in SPD, particularly concerning the cerebellum, the analysis focused on this brain region due to its involvement in sensorimotor and affective functions. The participants of the present study received affective (caress-like), which is typically perceived as pleasant and can be passively enjoyed. A total of 132 female participants (70 patients with SPD, 62 healthy controls) received affective and nonaffective touch to their forearms (slow vs. fast brushing) during functional magnetic resonance imaging. This tactil

SUBMITTER: Wabnegger A 

PROVIDER: S-EPMC10844139 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature