In silico exploration of hypothetical proteins in Neisseria gonorrhoeae for identification of therapeutic targets.

ABSTRACT: Neisseria gonorrhoeae, a World Health Organization (WHO) declared superbug and the second-most frequent cause of bacterial sexually transmitted infections worldwide is responsible for gonorrhea. Hypothetical proteins are gene products that are predicted to be encoded by a particular gene based on the DNA sequence, but their specific functions and characteristics have not been experimentally determined or verified. In the context of this research, annotating hypothetical proteins is crucial for identifying their potential as therapeutic targets. Without proper annotation, these proteins would remain vague, hindering efforts to understand their roles in disease. The methodology used aims to bridge this gap by employing algorithm-based tools and software to annotate hypothetical protei

SUBMITTER: Lakhanpal G 

PROVIDER: S-EPMC10844189 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature