Twenty years of participation of racialised groups in type 2 diabetes randomised clinical trials: a meta-epidemiological review.

ABSTRACT:

Aims/hypothesis

Type 2 diabetes mellitus prevalence is increasing globally and the greatest burden is borne by racialised people. However, there are concerns that the enrolment of racialised people into RCTs is limited, resulting in a lack of ethnic and racial diversity. This may differ depending whether an RCT is government funded or industry funded. The aim of this study was to review the proportions of racialised and white participants included in large RCTs of type 2 diabetes pharmacotherapies relative to the disease burden of type 2 diabetes in these groups.

Methods

The Ovid MEDLINE database was searched from 1 January 2000 to 31 December 2020. English language reports of RCTs of type 2 diabetes pharmacotherapies published in select medical journals were included. Studi

SUBMITTER: Ahmed R 

PROVIDER: S-EPMC10844363 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature