What underlies sex differences in heart failure onset within the first year after a first myocardial infarction?

ABSTRACT:

Background

Women are more likely to develop heart failure (HF) after myocardial infarction. However, diagnosis and reperfusion are often delayed.

Objectives

To compare the prevalence of HF after primary percutaneous coronary intervention (PPCI)-treated ST segment myocardial infarction (STEMI) between sexes and to study its associations with comorbidities, infarct size, and left ventricular (LV) systolic and diastolic dysfunctions (DD).

Methods

The patients with PPCI-treated anterior STEMI, from the CIRCUS study cohort, were followed up for 1 year and HF events were recorded. Evaluation of ejection fraction (LVEF) and DD were performed at baseline and at 1 year. The elevated LV filling pressure (LVFP) included Grades 2 and 3 DD.

Results

Of the 791 patients from

SUBMITTER: Leboube S 

PROVIDER: S-EPMC10844509 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature