Accelerometer-based physical activity is associated with the gut microbiota in 8416 individuals in SCAPIS.

ABSTRACT:

Background

Previous population-based studies investigating the relationship between physical activity and the gut microbiota have relied on self-reported activity, prone to reporting bias. Here, we investigated the associations of accelerometer-based sedentary (SED), moderate-intensity (MPA), and vigorous-intensity (VPA) physical activity with the gut microbiota using cross-sectional data from the Swedish CArdioPulmonary bioImage Study.

Methods

In 8416 participants aged 50-65, time in SED, MPA, and VPA were estimated with hip-worn accelerometer. Gut microbiota was profiled using shotgun metagenomics of faecal samples. We applied multivariable regression models, adjusting for sociodemographic, lifestyle, and technical covariates, and accounted for multiple testing.

Finding

SUBMITTER: Baldanzi G 

PROVIDER: S-EPMC10844941 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature