Risk of Stroke and Myocardial Infarction Among Initiators of Triptans.

ABSTRACT:

Importance

Triptans are contraindicated in patients with ischemic heart disease or previous myocardial infarction, and caution is advised when prescribing these drugs to patients with vascular risk factors. However, controlled observational studies have either shown no association or an apparent lower risk, possibly owing to a channeling of triptans to individuals at low risk of cardiovascular outcomes, and it remains unclear whether avoiding triptan treatment for these patients is meaningful.

Objective

To establish whether an association between triptans and ischemic events could be demonstrated using a self-controlled design because this type of design is robust to the previously mentioned type of confounding.

Design, setting, and participants

All people in nationwi

SUBMITTER: Petersen CL 

PROVIDER: S-EPMC10845042 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature