Preschool Depression and Hippocampal Volume: The Moderating Role of Family Income.

ABSTRACT:

Objective

Depression and low socioeconomic status have both been associated with hippocampal volume alterations. Whether these factors interact to predict neurobehavioral outcomes has not been adequately studied. The authors investigated family income as a moderator of the relationship between depression and hippocampal volume in a longitudinal sample.

Method

Longitudinal behavioral data, beginning at preschool age, and behavioral and neuroimaging data from school age to adolescence were used to assess the impact of preschool only and total preschool to adolescent depression symptoms on hippocampal volumes using family income as a moderator (N = 176).

Results

Depression severity during the preschool period interacted with family income to predict hippocampal volumes a

SUBMITTER: Herzberg MP 

PROVIDER: S-EPMC10845235 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature