The clinical and neuroimaging differences between vascular parkinsonism and Parkinson's disease: a case-control study.

ABSTRACT:

Background

Parkinson's disease (PD) and vascular parkinsonism (VaP) have highly overlapping phenotypes, and different prognosis. This study comprehensively investigated the clinical, brain MRI and transcranial sonography differences between VaP and PD.

Methods

Forty-eight patients with PD, 27 patients with VaP, and 29 healthy controls were compared. All patients were assessed using the MDS-UPDRS, Berg Balance Scale (BBS), Ten-Meter Walking Test (10-MWT), Time Up and Go Test, and Non-Motor Symptoms Scale. Beck Depression Inventory, PD questionnaire- 39, international urine incontinence scale, cognitive assessment scales, MRI brain and transcranial colour-coded doppler. The study was registered on clinical-Trial.gov (NCT04308135) on 03/12/2020.

Results

VaP patients show

SUBMITTER: George P 

PROVIDER: S-EPMC10845551 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature