Investigation on submicron particle separation and deflection using tilted-angle standing surface acoustic wave microfluidics.

ABSTRACT: With the development of in vitro diagnostics, extracting submicron scale particles from mixed body fluids samples is crucial. In recent years, microfluidic separation has attracted much attention due to its high efficiency, label-free, and inexpensive nature. Among the microfluidic-based separation, the separation based on ultrasonic standing waves has gradually become a powerful tool. A microfluid environment containing a tilted-angle ultrasonic standing surface acoustic wave (taSSAW) field has been widely adapted and designed to separate submicron particles for biochemical applications. This paper investigated submicron particle defection in microfluidics using taSSAWs analytically. Particles with 0.1-1 μm diameters were analyzed under acoustic pressure, flow rate, tilted angle, and SSAW

SUBMITTER: Peng T 

PROVIDER: S-EPMC10845702 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature