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Colorectal cancer pre-diagnostic symptoms are associated with anatomic cancer site.


ABSTRACT:

Background

Signs and red flag symptoms in colorectal cancer (CRC) patients who are below the recommended screening age are often overlooked, leading to delayed diagnosis and worse prognosis. This study investigates how patient pre-diagnostic symptoms are associated with anatomic site of their cancer and whether the association varies by age at CRC diagnosis.

Methods

We ascertained CRC patients' experienced symptoms and screening through medical abstractions from an ongoing population-based study of CRC patients identified through a SEER cancer registry (N = 626). We used logistic regression to estimate odds ratios and 95% confidence intervals for the association between symptoms and CRC anatomic site. Additional analyses were stratified by age at diagnosis. Early-onset was d

SUBMITTER: Briggs NL 

PROVIDER: S-EPMC10845784 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature