Molecular characterization of carbapenemase-producing Enterobacterales in a tertiary hospital in Lima, Peru.

ABSTRACT: Carbapenemase-producing Enterobacterales (CPE) are a growing threat to global health and the economy. Understanding the interactions between resistance and virulence mechanisms of CPE is crucial for managing difficult-to-treat infections and informing outbreak prevention and control programs. Here, we report the characterization of 21 consecutive, unique clinical isolates of CPE collected in 2018 at a tertiary hospital in Lima, Peru. Isolates were characterized by phenotypic antimicrobial susceptibility testing and whole-genome sequencing to identify resistance determinants and virulence factors. Seven Klebsiella pneumoniae isolates were classified as extensively drug-resistant. The remaining Klebsiella, Enterobacter hormaechei, and Escherichia coli isolates wer

SUBMITTER: Cuicapuza D 

PROVIDER: S-EPMC10846045 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature