Bleomycin reduces Vairimorpha (Nosema) ceranae infection in honey bees with some evident host toxicity.

ABSTRACT: Microsporidia cause disease in many beneficial insects, including honey bees, yet few pathogen control tools are available for protecting these important organisms against infection. Some evidence suggests that microsporidia possess a reduced number of genes encoding DNA repair proteins. We hypothesized that microsporidia would thus be susceptible to treatment with DNA-damaging agents and tested this hypothesis using a novel, rapid method for achieving robust and homogenous experimental infection of large numbers of newly emerged honey bees with one of its microsporidia pathogens, Vairimorpha (Nosema) ceranae. In carrying out these experiments, we found this novel V. ceranae inoculation method to have similar efficacy as other traditional methods. We show that t

SUBMITTER: Parrella P 

PROVIDER: S-EPMC10846157 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature