A shift between mineral and nonmineral sources of iron and sulfur causes proteome-wide changes in Methanosarcina barkeri.

ABSTRACT: Iron (Fe) and sulfur (S) are required elements for life, and changes in their availability can limit the ecological distribution and function of microorganisms. In anoxic environments, soluble Fe typically exists as ferrous iron [Fe(II)] and S as sulfide (HS^-). These species exhibit a strong affinity that ultimately drives the formation of sedimentary pyrite (FeS₂). Recently, paradigm-shifting studies indicate that Fe and S in FeS₂ can be made bioavailable by methanogens through a reductive dissolution process. However, the impact of the utilization of FeS₂, as opposed to canonical Fe and S sources, on the phenotype of cells is not fully understood. Here, shotgun proteomics was utilized to measure changes in the phenotype of Methanosarcina bar

SUBMITTER: Fausset H 

PROVIDER: S-EPMC10846266 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature