Modeling BMI z score lability during childhood as a function of child temperament and genetic risk for obesity.

ABSTRACT:

Objective

This study aimed to examine whether child genetic risk for obesity and temperament (i.e., negative affectivity, effortful control) accounted for stability versus lability in children's weight status (BMI z score) over time.

Methods

A total of 561 adopted children (42% female; 56% Caucasian, 13% African American, 11% Latino, and 20% other) and their birth and adoptive parents were followed from birth to age 9 years. The multilevel location-scale model was used to examine whether child genetic risk for obesity and temperament were related to differences in level and lability in child BMI z scores over time.

Results

For the full sample, higher levels of child negative affectivity were associated with greater BMI z score lability, whereas higher levels of effort

SUBMITTER: Liu C 

PROVIDER: S-EPMC10846492 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature