Impact of interstitial lung disease on left ventricular myocardial function.

ABSTRACT:

Background

Interstitial lung disease (ILD) comprises a wide variety of pulmonary parenchymal disorders within which progressive fibrosing ILD (PF-ILD) constitutes a phenotypic subset. By use of speckle tracking-based strain analysis we aimed to evaluate the degree of left ventricular (LV) dysfunction in progressive vs. non-progressive fibrosing ILD (non-PF-ILD).

Methods

A total of 99 ILD patients (mean age 63.7 ± 13.5 years, 37.4% female), composed of 50 PF-ILD and 49 non-PF-ILD patients, and 33 controls were prospectively enrolled and underwent conventional and speckle tracking echocardiography. Additional laboratory and pulmonary function testing, as well as six-minute walk test were performed.

Results

As compared to the non-PF-ILD cohort, PF-ILD patients exhibited

SUBMITTER: Stumpf MJ 

PROVIDER: S-EPMC10846726 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature