Caregiver Burden of Patients With Huntington's Disease in South Korea.

ABSTRACT:

Objective

This is the first prospective cohort study of Huntington's disease (HD) in Korea. This study aimed to investigate the caregiver burden in relation to the characteristics of patients and caregivers.

Methods

From August 2020 to February 2022, we enrolled patients with HD from 13 university hospitals in Korea. We used the 12-item Zarit Burden Interview (ZBI-12) to evaluate the caregiver burden. We evaluated the clinical associations of the ZBI-12 scores by linear regression analysis and investigated the differences between the low- and high-burden groups.

Results

Sixty-five patients with HD and 45 caregivers were enrolled in this cohort study. The average age at onset of motor symptoms was 49.3 ± 12.3 years, with an average cytosine-adenine-guanine (CAG)n of 42

SUBMITTER: Lee CY 

PROVIDER: S-EPMC10846961 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature