Comparative Olfactory Profiles in Parkinson's Disease and Drug-Induced Parkinsonism.

ABSTRACT:

Objective

Drug-induced parkinsonism (DIP) is a frequently encountered diagnostic possibility when considering Parkinson's disease (PD). While olfactory dysfunction is a common clinical feature in PD, the comparison of olfactory function between the two conditions remains insufficient. This study aimed to compare olfactory function, including threshold, discrimination, and identification (TDI) profiles, between PD and DIP.

Methods

Consecutive patients with drug-naïve PD (n = 78) or DIP (n = 31) confirmed through dopamine transporter imaging were enrolled in this study. The YSK olfactory function (YOF) test, composed of TDI domains culturally familiar odorants to Koreans, was administered to all patients.

Results

In the study population, patients with DIP were significa

SUBMITTER: Kwak IH 

PROVIDER: S-EPMC10846967 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature