Parkinson's Disease, Impulsive-Compulsive Behaviors, and Health-Related Quality of Life.

ABSTRACT:

Objective

A large body of literature has examined the links between the use of dopamine replacement therapy (DRT) in Parkinson's disease (PD) and the development of "impulsive-compulsive behaviors (ICBs)." Little is known regarding the link between the development of ICBs and health-related quality of life (HRQOL). We aimed to explore the factors that are associated with poorer HRQOL, especially in relation to DRT-induced ICBs, in a sample of PD patients.

Methods

This PARKADD (PARK: PARKinson's disease; ADD: behavioral ADDictions) study was a prospective case‒control study initially designed to assess the factors associated with ICBs in PD patients. A prospective clinical follow-up was added, aiming to capture the long-term evolution of HRQOL in relation to ICBs occurring or

SUBMITTER: Grall-Bronnec M 

PROVIDER: S-EPMC10846971 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature