Circulating ketone bodies and mortality in heart failure: a community cohort study.

ABSTRACT:

Background

The relationship between ketone bodies (KB) and mortality in patients with heart failure (HF) syndrome has not been well established.

Objectives

The aim of this study is to assess the distribution of KB in HF, identify clinical correlates, and examine the associations between plasma KB and all-cause mortality in a population-based HF cohort.

Methods

The plasma KB levels were measured by nuclear magnetic resonance spectroscopy. Multivariable linear regression was used to examine associations between clinical correlates and KB levels. Proportional hazard regression was employed to examine associations between KB (represented as both continuous and categorical variables) and mortality, with adjustment for several clinical covariates.

Results

Among the 1

SUBMITTER: Oyetoro RO 

PROVIDER: S-EPMC10847221 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature