Third ventricular width by transcranial sonography is associated with cognitive impairment in Parkinson's disease.

ABSTRACT:

Background

One-fourth of Parkinson's disease (PD) patients suffer from cognitive impairment. However, few neuroimaging markers have been identified regarding cognitive impairment in PD.

Objective

This study aimed to explore the association between third ventricular width by transcranial sonography (TCS) and cognitive decline in PD.

Method

Participants with PD were recruited from one medical center in China. Third ventricular width was assessed by TCS, and cognitive function was analyzed by the Mini-Mental State Examination (MMSE). Receiver operating characteristic (ROC) analysis and Cox model analysis were utilized to determine the diagnostic and predictive accuracy of third ventricular width by TCS for cognitive decline in PD patients.

Result

A total of 174 PD

SUBMITTER: Gao HL 

PROVIDER: S-EPMC10848047 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature