White matter structural topologic efficiency predicts individual resistance to sleep deprivation.

ABSTRACT:

Background

Sleep deprivation (SD) is commonplace in modern society and there are large individual differences in the vulnerability to SD. We aim to identify the structural network differences based on diffusion tensor imaging (DTI) that contribute to the individual different vulnerability to SD.

Methods

The number of psychomotor vigilance task (PVT) lapses was used to classify 49 healthy subjects on the basis of whether they were vulnerable or resistant to SD. DTI and graph theory approaches were used to investigate the topologic organization differences of the brain structural connectome between SD-vulnerable and -resistant individuals. We measured the level of global efficiency and clustering in rich club and non-rich club organizations.

Results

We demonstrated that

SUBMITTER: Guo F 

PROVIDER: S-EPMC10848061 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature