Age-Dependent Variations in Kawasaki Disease Incidence in Japan.

ABSTRACT:

Importance

The etiology of Kawasaki disease (KD) remains elusive, with immunologic and epidemiologic data suggesting different triggers in individuals who are genetically susceptible. KD remains the most common cause of acquired heart disease in pediatric patients, and Japan is the country of highest incidence, with an increasing number of cases.

Objective

To investigate whether an analysis of the epidemiologic KD record in Japan stratified by age and prefecture (subregion) may yield new clues regarding mechanisms of exposure to etiologic agents associated with KD.

Design, setting, and participants

This cross-sectional study was conducted using a dataset of patients with KD with detailed information on location and age at onset created through nationwide surveys of ho

SUBMITTER: DeHaan LL 

PROVIDER: S-EPMC10848069 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature