Functional magnetic resonance imaging study during resting state and visual oddball task in mild cognitive impairment.

ABSTRACT:

Background

Amnestic mild cognitive impairment (aMCI) is a transitional state between normal aging and dementia, and identifying early biomarkers is crucial for disease detection and intervention. Functional magnetic resonance imaging (fMRI) has the potential to identify changes in neural activity in MCI.

Methods

We investigated neural activity changes in the visual network of the aMCI patients (n:20) and healthy persons (n:17) using resting-state fMRI and visual oddball task fMRI. We used independent component analysis to identify regions of interest and compared the activity between groups using a false discovery rate correction.

Results

Resting-state fMRI revealed increased activity in the areas that have functional connectivity with the visual network, including th

SUBMITTER: Kemik K 

PROVIDER: S-EPMC10848090 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature