Hyper-IgE syndrome: a case report.

ABSTRACT:

Introduction and importance

Hyper-IgE syndrome (HIES), also known as Job syndrome, is a rare primary immunodeficiency disorder characterized by elevated serum IgE levels, recurrent infections, and various clinical features. Early diagnosis, prompt management of infections, and supportive care are essential in improving outcomes for individuals with HIES. Genetic testing, including STAT3 gene sequencing, plays a crucial role in confirming the diagnosis. Further research is needed to enhance our understanding of HIES and develop targeted therapies to improve the quality of life for affected individuals.

Case presentation

This case report presents the clinical features and management of a 37-year-old male with HIES, diagnosed at the age of 2 due to recurrent cold abscesses caus

SUBMITTER: Dave T 

PROVIDER: S-EPMC10849427 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature