Genomic Landscape of NSCLC in the Republic of Ireland.

ABSTRACT:

Introduction

The identification of genomic "targets" through next-generation sequencing (NGS) of patient's NSCLC tumors has resulted in a rapid expansion of targeted treatment options for selected patients. This retrospective study aims to identify the proportion of patients with advanced NSCLC in the Republic of Ireland whose tumors harbor actionable genomic alterations through broad NGS panel testing.

Methods

Institutional review board approval was obtained before study initiation. Patients with NSCLC whose tumors underwent genomic testing through the largest available NGS panel at a nationally funded Cancer Molecular Diagnostics laboratory (St. James's Hospital) between June 2017 and June 2022 were identified. Patient demographics and tumor-related data were collected by

SUBMITTER: Keogh RJ 

PROVIDER: S-EPMC10850121 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature