[Immunotherapy against gliomas].

ABSTRACT:

Background

Gliomas represent the most frequent malignant primary brain tumors in adults. Despite multimodal treatment concepts involving surgery, irradiation and chemotherapy, the prognosis remains poor and they are incurable. Recent insights into the interactions between the immune system and the central nervous system as well as breakthroughs in the results of other cancer types have led to the fact that various immunotherapeutic approaches against gliomas have also been investigated and in some cases specifically developed.

Objective

This article provides an overview of the current status of different immunotherapeutic concepts against gliomas, highlighting the advantages, disadvantages, and challenges. Additionally, it provides an overview of currently ongoing immunother

SUBMITTER: Sahm K 

PROVIDER: S-EPMC10850214 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature