Association of Muscle Mass Loss with Diabetes Development in Liver Transplantation Recipients.

ABSTRACT:

Backgruound

Post-transplant diabetes mellitus (PTDM) is one of the most significant complications after transplantation. Patients with end-stage liver diseases requiring transplantation are prone to sarcopenia, but the association between sarcopenia and PTDM remains to be elucidated. We aimed to investigate the effect of postoperative muscle mass loss on PTDM development.

Methods

A total of 500 patients who underwent liver transplantation at a tertiary care hospital between 2005 and 2020 were included. Skeletal muscle area at the level of the L3-L5 vertebrae was measured using computed tomography scans performed before and 1 year after the transplantation. The associations between the change in the muscle area after the transplantation and the incidence of PTDM was investiga

SUBMITTER: Lee S 

PROVIDER: S-EPMC10850281 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature