Roles of the cerebellar vermis in predictive postural controls against external disturbances.

ABSTRACT: The central nervous system predictively controls posture against external disturbances; however, the detailed mechanisms remain unclear. We tested the hypothesis that the cerebellar vermis plays a substantial role in acquiring predictive postural control by using a standing task with floor disturbances in rats. The intact, lesioned, and sham groups of rats sequentially underwent 70 conditioned floor-tilting trials, and kinematics were recorded. Six days before these recordings, only the lesion group underwent focal suction surgery targeting vermal lobules IV-VIII. In the naïve stage of the sequential trials, the upright postures and fluctuations due to the disturbance were mostly consistent among the groups. Although the pattern of decrease in postural fluctuation due to learning correspon

SUBMITTER: Konosu A 

PROVIDER: S-EPMC10850480 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature