Impact of Environmental Exposures on Human Breast Milk Lipidome in Future Immune-Mediated Diseases.

ABSTRACT: The composition of human breast milk (HBM) exhibits significant variability both between individuals and within the same individual. While environmental factors are believed to play a role in this variation, their influence on breast milk composition remains inadequately understood. Herein, we investigate the impact of environmental factors on HBM lipid composition in a general population cohort. The study included mothers (All Babies In Southeast Sweden study) whose children later progressed to one or more immune-mediated diseases later in life: type 1 diabetes (n = 9), celiac disease (n = 24), juvenile idiopathic arthritis (n = 9), inflammatory bowel disease (n = 7), hypothyroidism (n = 6), and matched controls (n = 173). Lipidome of HBM was char

SUBMITTER: Hyotylainen T 

PROVIDER: S-EPMC10851438 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature