Development and validation of a nomogram for predicting overall survival in patients with sinonasal mucosal melanoma.

ABSTRACT:

Background

Sinonasal mucosal melanoma (SNMM) is a relatively rare malignant tumour with a poor prognosis. This study was designed to identify prognostic factors and establish a nomogram model to predict the overall survival (OS) of patients with SNMM.

Methods

A total of 459 patients with SNMM were selected from the Surveillance, Epidemiology, and End Results (SEER) database as the training cohort. Univariate and multivariate Cox regression analyses were used to screen for independent factors associated with patient prognosis and develop the nomogram model. In addition, external validation was performed to evaluate the effectiveness of the nomogram with a cohort of 34 patients with SNMM from Peking Union Medical College Hospital.

Results

The median OS in the cohort fro

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC10851497 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature