MicroRNA signatures differentiate types, grades, and stages of breast invasive ductal carcinoma (IDC): miRNA-target interacting signaling pathways.

ABSTRACT:

Background

Invasive ductal carcinoma (IDC) is the most common form of breast cancer which accounts for 85% of all breast cancer diagnoses. Non-invasive and early stages have a better prognosis than late-stage invasive cancer that has spread to lymph nodes. The involvement of microRNAs (miRNAs) in the initiation and progression of breast cancer holds great promise for the development of molecular tools for early diagnosis and prognosis. Therefore, developing a cost effective, quick and robust early detection protocol using miRNAs for breast cancer diagnosis is an imminent need that could strengthen the health care system to tackle this disease around the world.

Methods

We have analyzed putative miRNAs signatures in 100 breast cancer samples using two independent high fidelity

SUBMITTER: Verma VK 

PROVIDER: S-EPMC10851529 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature