Intra-abdominal pressure and residual renal function decline in peritoneal dialysis: a threshold-based investigation.

ABSTRACT:

Background

The potential impact of elevated intra-abdominal pressure (IAP) on residual renal function (RRF) has not been determined. The objective of this study was to investigate the relationship between IAP and the rate of RRF decline in newly initiated peritoneal dialysis (PD) patients, and to identify the optimal IAP threshold value for delaying the deterioration of RRF.

Methods

A cohort of 62 newly initiated PD patients who completed both 6- and 12-month follow-up evaluations was obtained using the Durand method. A logistic regression model was used to identify variables associated with a rapid decline in RRF. Receiver operating characteristic (ROC) curves were generated to determine the optimal threshold value. Another retrospective cohort analysis was performed to val

SUBMITTER: Zhang J 

PROVIDER: S-EPMC10851793 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature