Scalp and hippocampal sleep correlates of memory function in drug-resistant temporal lobe epilepsy.

ABSTRACT: Seminal animal studies demonstrated the role of sleep oscillations such as cortical slow waves, thalamocortical spindles, and hippocampal ripples in memory consolidation. In humans, whether ripples are involved in sleep-related memory processes is less clear. Here, we explored the interactions between sleep oscillations (measured as traits) and general episodic memory abilities in 26 adults with drug-resistant temporal lobe epilepsy who performed scalp-intracranial electroencephalographic recordings and neuropsychological testing, including two analogous hippocampal-dependent verbal and nonverbal memory tasks. We explored the relationships between hemispheric scalp (spindles, slow waves) and hippocampal physiological and pathological oscillations (spindles, slow waves, ripples, and epilept

SUBMITTER: Latreille V 

PROVIDER: S-EPMC10851866 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature