Risk Factors for the Development of New-Onset Persistent Atrial Fibrillation: Subanalysis of the VITAL Study.

ABSTRACT:

Background

Sustained forms of atrial fibrillation (AF) are associated with lower treatment success rates and poorer prognosis compared with paroxysmal AF. Yet, little is known about risk factors that predispose to persistent AF on initial presentation. Our objective was to define risk factors associated with new-onset persistent AF.

Methods

We prospectively examined the differential associations between lifestyle, clinical, and socioeconomic risk factors and AF pattern (persistent versus paroxysmal) at the time of diagnosis among 25 119 participants without a history of cardiovascular disease, AF, or cancer in the VITAL rhythm study (Vitamin D and Omega-3).

Results

During a median follow-up of 5.3 years, 900 participants developed AF and 346 (38.4%) were classified as

SUBMITTER: Middeldorp ME 

PROVIDER: S-EPMC10852030 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature