Association between systemic immune-inflammation index and chronic kidney disease: A population-based study.

ABSTRACT:

Background

Systemic immune-inflammation index (SII) is a new indicator of inflammation, and chronic kidney disease (CKD) has a connection to inflammation. However, the relationship between SII and CKD is still unsure. The aim of this study was whether there is an association between SII and CKD in the adult US population.

Methods

Data were from the National Health and Nutrition Examination Survey (NHANES) in 2003-2018, and multivariate logistic regression was used to explore the independent linear association between SII and CKD. Smoothing curves and threshold effect analyses were utilized to describe the nonlinear association between SII and CKD.

Results

The analysis comprised 40,660 adults in total. After adjusting for a number of factors, we found a positive associ

SUBMITTER: Li L 

PROVIDER: S-EPMC10852278 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature