Growth and adiposity in newborns study (GAINS): The influence of prenatal DHA supplementation protocol.

ABSTRACT:

Background

Obesity and central fat mass (FM) accrual drive disease development and are related to greater morbidity and mortality. Excessive gestational weight gain (GWG) increases fetal fat accretion resulting in greater offspring FM across the lifespan. Studies associate greater maternal docosahexaenoic acid (DHA) levels with lower offspring FM and lower visceral adipose tissue during childhood, however, most U.S. pregnant women do not consume an adequate amount of DHA. We will determine if prenatal DHA supplementation is protective for body composition changes during infancy and toddlerhood in offspring exposed to excessive GWG.

Methods and design

Infants born to women who participated in the Assessment of DHA on Reducing Early Preterm Birth randomized controlled trial (A

SUBMITTER: Hull HR 

PROVIDER: S-EPMC10852997 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature