Diagnostic accuracy of MRI, CT, and [¹⁸F]FDG-PET-CT in detecting lymph node metastases in clinically early-stage cervical cancer - a nationwide Dutch cohort study.

ABSTRACT:

Objectives

Imaging is increasingly used to assess lymph node involvement in clinically early-stage cervical cancer. This retrospective study aimed to evaluate the diagnostic accuracy of MRI, CT, and [¹⁸F]FDG-PET-CT.

Methods

Women with International Federation of Gynaecology and Obstetrics (FIGO) 2009 stage IA2-IIA cervical cancer and pretreatment imaging between 2009 and 2017 were selected from the Netherlands Cancer Registry. Patient-based and region-based (i.e. pelvic and common iliac) nodal status was extracted from radiology reports. Pathology results were considered the reference standard for calculating accuracy indices. Multiple imputation was used for missing pathology to limit verification bias risk.

Results

Nodal assessment was performed in 1676 p

SUBMITTER: Olthof EP 

PROVIDER: S-EPMC10853153 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature