Standardizing the estimation of ischemic regions can harmonize CT perfusion stroke imaging.

ABSTRACT:

Objectives

We aimed to evaluate the real-world variation in CT perfusion (CTP) imaging protocols among stroke centers and to explore the potential for standardizing vendor software to harmonize CTP images.

Methods

Stroke centers participating in a nationwide multicenter healthcare evaluation were requested to share their CTP scan and processing protocol. The impact of these protocols on CTP imaging was assessed by analyzing data from an anthropomorphic phantom with center-specific vendor software with default settings from one of three vendors (A-C): IntelliSpace Portal, syngoVIA, and Vitrea. Additionally, standardized infarct maps were obtained using a logistic model.

Results

Eighteen scan protocols were studied, all varying in acquisition settings. Of these protocol

SUBMITTER: Peerlings D 

PROVIDER: S-EPMC10853359 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature