Dataset Information

RNA m⁶ A Methylation Suppresses Insect Juvenile Hormone Degradation to Minimize Fitness Costs in Response to A Pathogenic Attack.

ABSTRACT: Bioinsecticides and transgenic crops based on the bacterial pathogen Bacillus thuringiensis (Bt) can effectively control diverse agricultural insect pests, nevertheless, the evolution of resistance without obvious fitness costs has seriously eroded the sustainable use of these Bt products. Recently, it has been discovered that an increased titer of juvenile hormone (JH) favors an insect host (Plutella xylostella) to enhance fitness whilst resisting the Bt pathogen, however, the underlying regulatory mechanisms of the increased JH titer are obscure. Here, the involvement of N⁶ -methyladenosine (m⁶ A) RNA modification in modulating the availability of JH in this process is defined. Specifically, it is found that two m⁶ A methyltransferase subunit genes, PxMet

SUBMITTER: Guo Z

PROVIDER: S-EPMC10853702 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Dataset Information

RNA m⁶ A Methylation Suppresses Insect Juvenile Hormone Degradation to Minimize Fitness Costs in Response to A Pathogenic Attack.

OmicsDI is part of the ELIXIR infrastructure

Tweets

Dataset Information

RNA m6 A Methylation Suppresses Insect Juvenile Hormone Degradation to Minimize Fitness Costs in Response to A Pathogenic Attack.

OmicsDI is part of the ELIXIR infrastructure

Tweets

RNA m⁶ A Methylation Suppresses Insect Juvenile Hormone Degradation to Minimize Fitness Costs in Response to A Pathogenic Attack.