Anti‑angiogenic and cytotoxic evaluation of green‑synthesized Fe₂ZnO₄ nanoparticles against MCF‑7 cell line.

ABSTRACT: The use of plants for nanoparticle (NP) synthesis, grounded in green chemistry principles, is an environmentally friendly and economically viable approach. In the present study, the leaf extract of Elaeagnus angustifolia L. was used as a biosynthetic agent to generate bimetallic zinc oxide NPs. The present study investigated the effect of ZnO NPs on anti-angiogenesis and cell migration. Various bimetallic NPs, including zinc-iron oxide and nickel-zinc oxide, underwent characterization through Fourier-transform infrared spectroscopy and X-ray Diffraction within the 25-65˚ range. Confirmation of NP formation was determined by identifying the surface plasmon resonance peak. MTT assay was used to determine the cytotoxic properties of E. angustifolia L. extracts, ZnO NPs and assoc

SUBMITTER: Al-Zabin A 

PROVIDER: S-EPMC10853757 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature